Helene D. Gayle became the first CEO of the newly created McKinsey Social Initiative in July 2015. Born and raised in Buffalo, New York, she received her B.A. from Barnard College of Columbia University, her M.D. from the University of Pennsylvania, and her M.P.H. from Johns Hopkins University. After completing her residency in pediatric medicine at the Children’s Hospital National Medical Center in Washington, D.C., she entered the Epidemic Intelligence Service at the Centers for Disease Control and Prevention (CDC), followed by a residency in preventive medicine, and then remained at CDC as a staff epidemiologist. At CDC, she studied problems of malnutrition in children in the United States and abroad, evaluating and implementing child survival programs in Africa, and working on HIV/AIDS research, programs, and policy. Dr. Gayle also served as the AIDS coordinator and chief of the HIV/AIDS division for the U.S. Agency for International Development; director for the National Center for HIV, STD, and TB Prevention, CDC; director of CDC’s Washington office; and health consultant to international agencies including the World Health Organization, UNICEF, the World Bank, and UNAIDS. After leaving CDC, she served as the director of the HIV, TB, and reproductive health program for the Bill and Melinda Gates Foundation. Prior to her current position, she was the president and CEO of CARE for almost a decade.